A Short Synthesis of Rhaponticin and its 3”-Fluoroanalog via a Wittig/Heck-Mizoroki Route
نویسندگان
چکیده
Rhaponticin and its 3”-fluoroanalog have been prepared from easily accessible starting materials. The key step of these syntheses is the silver carbonate-mediated glycosidation reaction employed for the selective formation of a β -glycosidic bond. A palladium acetate-catalyzed Heck-Mizoroki reaction in triethanolamine established an (E) configuration in the stilbene with simultaneous deprotection of the carbohydrate.
منابع مشابه
Synthesis, Characterization and Catalytic Study of a Novel Binuclear Paddle-wheel Palladium(II) Complex in the Mizoroki-Heck Reaction
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